Count: 40
| Race Date | Class | Series | Race | Car Count | Winner | Start | Story |
| Saturday, April 17, 2021 | Wing | | Season Opener | 37 | Sheldon Haudenschild | 14 | Sheldon Haudenschild Steals One on Last Lap From Scelzi for $5,000 at Knoxville! | |
| Wing 360 | | Season Opener | 27 | Jamie Ball | 2 | Jamie Ball Cruises to 360 Win | |
| Saturday, April 24, 2021 | Wing | | | 24 | Austin McCarl | 3 | Austin McCarl Tops Knoxville with Emotional Win! | |
| Wing 360 | | | 37 | Josh Higday | 2 | Josh Higday Wins for First Time Since 2010 in 360’s | |
| Saturday, May 1, 2021 | Wing | | | 21 | Lynton Jeffrey | 2 | Lynton Jeffrey Tops Them All at Knoxville! | |
| Wing 360 | | | 24 | Clint Garner | 2 | Clint Garner Grabs Career Win #41 in 360’s | |
| Saturday, May 22, 2021 | Wing | | | 20 | Brian Brown | 3 | Brian Brown Sweeps Dual Features, Sets New One-Lap Record at Knoxville! | |
| Wing | | Make-up from 5/15 | 19 | Brian Brown | 6 | Brian Brown Sweeps Dual Features, Sets New One-Lap Record at Knoxville! | |
| Wing 360 | | | 22 | Ryan Giles | 3 | Ryan Giles Wins 360 Thriller | |
| Saturday, May 29, 2021 | Wing | | | 31 | Brad Sweet | 4 | Brad Sweet Invades Knoxville for $5,000 Payday! | |
| Wing 360 | | | 24 | Jamie Ball | 6 | Jamie Ball Roars to Another 360 Win | |
| Saturday, June 5, 2021 | Wing | | | 29 | Gio Scelzi | 2 | Gio Scelzi Scintillating at Knoxville! | |
| Wing 360 | | | 28 | Clint Garner | 1 | Clint Garner Makes Hodnett/Swindell Tribute Pay Off in 360’s | |
| Friday, June 11, 2021 | Wing | WoO | | 39 | Carson Macedo | 3 | PERFECT TIMING: MACEDO GIVES JJR ANOTHER KNOXVILLE WIN ON FINAL RESTART | |
| Saturday, June 12, 2021 | Wing | WoO | | 39 | Carson Macedo | 1 | GET OUT THE BROOM: MACEDO & JJR SWEEP BROWNELLS BIG GUNS BASH WITH LAST-LAP PASS AT KNOXVILLE | |
| Wing 360 | | | 20 | Dylan Westbrook | 4 | Dylan Westbrook Wins Last Lap Thriller in the 360 Class As Well | |
| Friday, June 18, 2021 | Wing 360 | | | 31 | Jamie Ball | 10 | Jamie Ball and Carson McCarl Win 360 Barnburners at Knoxville! | |
| Wing 360 | | Make-up from 5/15 | 23 | Carson McCarl | 2 | Jamie Ball and Carson McCarl Win 360 Barnburners at Knoxville! | |
| Saturday, June 19, 2021 | Wing | | | 27 | Kerry Madsen | 4 | Kerry Madsen Joins Boss in Roaring to Knoxville Win! | |
| Saturday, July 3, 2021 | Wing | | | 26 | Justin Henderson | 1 | Justin Henderson Provides the Fireworks for $5,000 at Knoxville! | |
| Wing 360 | | | 25 | Cory Eliason | 5 | Cory Eliason Makes Late Pass for Second Career 360 Win | |
| Saturday, July 17, 2021 | Wing | | | 26 | Justin Henderson | 8 | Justin Henderson Brings Home the Beef, the Pork and $7,000 at Knoxville! | |
| Wing 360 | MPS | | 33 | Justin Henderson | 4 | Justin Henderson Brings Home the Beef, the Pork and $7,000 at Knoxville! | |
| Saturday, July 24, 2021 | Wing | | | 24 | Brian Brown | 1 | Brian Brown Earns $5,000 With Return to Victory Lane at Knoxville! | |
| Wing 360 | | | 31 | Clint Garner | 1 | Clint Garner Paces 360 Field | |
| Saturday, July 31, 2021 | Wing | AS | | 46 | Kerry Madsen | 3 | Kerry Madsen scores second consecutive All Star victory with Knoxville Raceway triumph | |
| Wing 360 | | | 40 | Gio Scelzi | 3 | Gio Scelzi is Dominant with 360 Win | |
| Thursday, August 5, 2021 | Wing 360 | ASCS | 360 Knoxville Nationals Prelim | 43 | Sam Hafertepe Jr | 6 | Sam Hafertepe Jr. Cruises to First Knoxville Win on Night #1 of My Place Hotels 360 Knoxville Nationals | |
| Friday, August 6, 2021 | Wing 360 | ASCS | 360 Knoxville Nationals Prelim | 47 | Gio Scelzi | 3 | ate Pass Nets Win for Gio Scelzi on Night #2 of My Place Hotels 360 Knoxville Nationals | |
| Saturday, August 7, 2021 | Wing 360 | ASCS | 360 Knoxville Nationals | 90 | Gio Scelzi | 4 | Gio Scelzi Wins Electrifying My Place Hotels 360 Knoxville Nationals! | |
| Sunday, August 8, 2021 | Wing | | Capitani Classic | 65 | David Gravel | 5 | David Gravel Emerges Victorious For Second Career Capitani Classic Win! | |
| Wednesday, August 11, 2021 | Wing | | Knoxville Nationals Prelim | 49 | David Gravel | 6 | David Gravel Continues Knoxville Roll in Nationals Opener! | |
| Thursday, August 12, 2021 | Wing | | Knoxville Nationals Prelim | 48 | Brian Brown | 4 | Brian Brown On Top On Night Two of the Knoxville Nationals! | |
| Friday, August 13, 2021 | Wing | | Knoxville Nationals Friday | 69 | Rico Abreu | 2 | Rico Abreu Wins; Anthony Macri, Shane Stewart and Brock Zearfoss Also Qualify for Knoxville Nationals Finale! | |
| Saturday, August 14, 2021 | Wing | WoO | Knoxville Nationals | 97 | Kyle Larson | 3 | Kyle Larson Achieves His Dream with Knoxville Nationals Win! | |
| Saturday, August 28, 2021 | Wing | | | 29 | Brian Brown | 4 | Brian Brown Wins Race, Davey Heskin Wins War in Crazy Night at Knoxville! | |
| Wing 360 | | | 26 | Scott Bogucki | 9 | Scott Bogucki Wins 360 Feature/Clint Garner Pulls Off Ninth Title | |
| Thursday, September 16, 2021 | Late Model | LOLM | Late Model Knoxville Nationals Prelim | 48 | Tyler Erb | 2 | TYLER ERB CLAIMS NIGHT ONE AT KNOXVILLE | |
| Friday, September 17, 2021 | Late Model | LOLM | Late Model Knoxville Nationals Prelim | 47 | Tyler Erb | 3 | TYLER ERB GOES BACK-TO-BACK IN KNOXVILLE PRELIMS | |
| Saturday, September 18, 2021 | Late Model | LOLM | Late Model Knoxville Nationals | 48 | Mike Marlar | 3 | MIKE MARLAR WINS A RECORD THIRD LUCAS OIL LATE MODEL KNOXVILLE NATIONALS | |
